Stereocontrolled Synthesis Of (+)-Iridomyrmecin And (-)-Isoiridomyrmecin From (-)-Limonene

Abstract

Trans-3,4-Disubstituted Cyclopentanone (3b), Obtained From (-)-Limonene Via Chiral Rh[(+)-Binap]Clo₄ Complex-Catalyzed Cyclization Of The 4-Pentenal (2), Could Be Converted Into The (+)-Iridomyrmecin(1a) And (-)-Isoiridomyrmecin (1b).

Key Words:

• (-)-Limonene
• Rhodium
• Cyclization
• Cyclopentanone
• (+)-Iridomyrmecin
• (-)-Isoiridomyrmecin