Inclusion Abilities of Bile Acids with Different Side Chain Length

Abstract

It was found that steroidal bile acids have greatly different inclusion abilities with decreasing or increasing their side chain length. Namely, the acids with intermediate side chains formed inclusion compounds with various organic compounds, while those with shorter or longer chains did not include so many. X-ray crystallographic studies clarified that the chains alter the hydrogen bonding networks among the host molecules, leading to the changes of the inclusion abilities and assembly modes.

Key Words:

• bile acids
• side chain length
• inclusion compounds
• inclusion ability
• crystal structures