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Abstract
“Dichloromethane” is included on the List of Priority Substances to be assessed under the Canadian Environmental Protection Act. Based upon estimation of the total average daily intake of dichloromethane from indoor air, ambient air, drinking water and food for various age groups in the Canadian general population, air (particularly indoor air) appears to be the most important source of exposure. Based upon the sufficient weight of evidence of carcinogenicity in experimental animals, dichloromethane is considered to be “probably carcinogenic to humans”. Based on the comparison of estimated exposure with quantitative estimates of cancer potency, the priority for analysis of options to reduce exposure in the general environment is considered to be low to moderate compared to that of other substances assessed in the Priority Substances program.
Notes
Author to whom correspondence or requests for the complete Assessment Report and (unpublished) Supporting Documentation should be addressed.