Extending the Hydrogen-bonding Array in ortho-Phenylenediamine Based Bis-ureas

Abstract

Two new ortho-phenylenediamine based bis-urea compounds have been synthesized with pendant amide groups. The stability constants of the new compounds with a variety of anionic guests have been measured by ¹H NMR titration techniques and compared to the parent bis-urea. The X-ray crystal structure of the acetate and benzoate complexes of a bis-amide functionalized system have been solved and reveal the receptor forming a dimer with two anions bound at the termini of the hydrogen bonded assembly.

Keywords:

• Anion receptors
• Amides
• Urea
• Crystallography

Acknowledgements

We would like to thank the EPSRC for a DTA studentship (SJB) and for use of the crystallographic facilities at the University of Southampton.