Clathrate tetraldehyde cavitand: single-crystal structure and NMR study

Abstract

The tetraldehyde cavitand, C₁₀₀H₈₈O₂₀, was synthesised as the penultimate stage of a procedure to obtain cavitand-capped porphyrins. The complete structural characterisation was performed by single-crystal X-ray diffraction studies, NMR and IR spectroscopy. The inclusion phenomena of the solvent molecules were confirmed using NMR spectroscopy. The structure is the first example of a clathrate having an aromatic tetraldehyde cavitand grown as a single crystal with acetonitrile at the lower rim of the molecule and methanol at the upper rim of the molecule.

Keywords:

• Tetraldehyde cavitand
• molecular recognition
• crystal structure
• NMR
• TGA

Acknowledgements

We gratefully acknowledge financial support by the DST-National Research Foundation, Centre of Excellence in Catalysis, c*change. Dr Hitesh M. Parekh is thankful the University of KwaZulu-Natal for postdoctoral fellowship. Dr Pramod B. Pansuriya would like to thank the DST-National Research Foundation, Centre of Excellence in Catalysis, c*change for a postdoctoral fellowship.

Disclosure statement

No potential conflict of interest was reported by the authors.

Additional information

Funding

This work was supported by the DST-National Research Foundation, Centre of Excellence in Catalysis, c*change.