Molecular recognition: New chiral metalloporphyrins as receptor models

Abstract

New chiral metalloporphyrins capable of multi-point recognition are prepared and their recognition behavior, especially chiral recognition, is studied. The first part of the paper is concerned with general formalism for multi-point recognition, where uniqueness of multi-point recognition, isolation of interaction in terms of free energy, enthalpy and entropy, and the meaning of these thermo- dynamic parameters are discussed. -Enantioselective binding of amino acid esters to two new chiral porphyrins is investigated by W-vis, NMR and IR spectroscopic methods. Chid recognition is achieved by combination of three recognition interactions between host and guest.