![Sample our Physical Sciences journals, sign in here to start your FREE access for 14 days]({"type":"image" , "src" : "/sda/110819/TOC-Subject-Sample-2021-Physical-Sciences.jpg"})
Abstract
Polymers able to recognize the female steroid hormone, β-estradiol, have been synthesized using molecular imprinting based on non-covalent interactions. A chromatographic study of the polymers demonstrated a strong dependence of the selectivity and strength of their interaction with analytes on the solvents used both as porogen and chromatographic mobile phase. Hydrogen bonding between the OH-group at C-17 of β-estradiol and methacrylic acid (the functional monomer of the polymer) plays a major role in the process of molecular recognition but hydrophobic and dipole-dipole interactions also contribute.