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Anxiety, Stress, & Coping
An International Journal
Volume 30, 2017 - Issue 3
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BRIEF REPORT

A meta-analysis of the relationship between anxiety and telomere length

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Pages 264-272 | Received 26 Apr 2016, Accepted 25 Oct 2016, Published online: 28 Nov 2016
 

ABSTRACT

Background and objectives: Telomeres are protective caps at the ends of chromosomes, and shorter telomeres are associated with poor physical health. The present study set out to consolidate the varying effect sizes found so far in studies of anxiety and telomere length.

Design and methods: A meta-analytic investigation of the relationship between anxiety and telomere length used information from 17 different samples comprising a total of 19,424 participants.

Results: The results showed a small but significant association, r = −.06, between higher anxiety and shorter telomeres. Studies comparing individuals diagnosed with an anxiety disorder with other individuals had a significant effect size, and studies that did not use this comparison threshold did not have a significant effect size.

Conclusions: Anxiety is associated with an important biomarker related to health. Future experimental studies that examine the impact of interventions intended to reduce anxiety in conjunction with measurement of telomere length can further clarify the impact of anxiety on telomere length.

Disclosure statement

No potential conflict of interest was reported by the authors.

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