Clinical assessment of the specificity of an adipsin rapid test for the diagnosis of preeclampsia

ABSTRACT

Objective: To evaluate the specificity of the adipsin rapid test in clinical practice for the diagnosis of preeclampsia (PE). Methods: A total of 1144 pregnant women were recruited in this study: 44 pregnant women with PE and 1100 healthy pregnancies as controls. Urine samples were collected and used, respectively, for the adipsin rapid test and the urinary dipstick test for protein detection. Sensitivity and specificity were calculated on the basis of the detection results. Results: In the 1144 women examined with the adipsin rapid test for PE diagnosis, the sensitivity and specificity were 93.2% and 98.8%, respectively; the total accuracy was 98.6%. For the 1144 women tested with urinary dipstick, the sensitivity and specificity were 93.2% and 40.5%, respectively; and the total accuracy was 42.5%. Conclusion: Both the adipsin rapid test and the urinary dipstick test are noninvasive and inexpensive rapid tests for the diagnosis of PE. However, the adipsin rapid test was proven more reliable since it had a higher sensitivity, specificity, and accuracy.

KEYWORDS:

• Adipsin
• adipsin rapid test
• preeclampsia
• specificity
• urine dipstick

Funding

This work was supported by a grant from Science and Technology Department of Sichuan Province (No. 2013SZ0004).

Additional information

Funding

This work was supported by a grant from Science and Technology Department of Sichuan Province (No. 2013SZ0004).