ABSTRACT
Objective
To evaluate obstetric and kidney outcomes in pregnancies with kidney transplantation.
Methods
We retrospectively reviewed 32 singleton pregnancies in kidney transplant recipients. Obstetric outcomes were explored according to the estimated glomerular filtration rates (eGFR) of patients.
Results
The incidences of fetal growth restriction, preeclampsia were 18.8% and 34.4%, respectively. There was a significant negative correlation between first-trimester eGFR and perinatal mortality (r = −0.546, p = .0.001) and composite adverse obstetric outcome (r = −0.415, p = .0.018).
Conclusion
The degree of transplanted kidney function impairment at the beginning of pregnancy is the major determinant of pregnancy outcome.
Disclosure statement
No potential conflict of interest was reported by the authors.
Statement of ethics
The study protocol was approved by the research institute’s committee on human research (52825153-604.01.01-72113)
Supplementary material
Supplemental data for this article can be accessed here.