Cardiovascular risk after hypertensive disorders of pregnancy in women with and without inheritable Thrombophilia

ABSTRACT

Aim of this study was to compare cardiovascular risk in women with and without inheritable thrombophilia after hypertensive disorders of pregnancy (HDP). Blood pressure, anthropometrics and blood samples were measured 9-13 years after early-onset (<34 weeks) HDP. Amongst the 114 women included, no differences in hypertension (31.1% vs. 33.7%, OR 0.90 95% CI (0.29–2.79)), body mass index > 25 kg/m² (43.8% vs. 53.1%, OR 0.69 95% CI (0.24–2.00)) or metabolic syndrome (18.8% vs. 13.3%, OR 1.51 95% CI (0.38–6.02)) were found. These data show similar cardiovascular risk profile in women with and without inheritable thrombophilia.

KEYWORDS:

• Preeclampsia
• placenta
• maternal morbidity and mortality

Acknowledgments

We thank all women for their participation in the original studies that have enabled us with our data on cardiovascular risk factors. We also thank A. Arduç for his help during the visits of all participants with inheritable thrombophilia in physical examination and blood sample collection.

Disclosure statement

The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the paper.