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Original

Lipofuscin-like fluorophores originated from malondialdehyde

Pages 1335-1338 | Received 29 May 2006, Published online: 07 Jul 2009
 

Abstract

The accumulation of fluorescent age pigment or lipofuscin is a frequently observed age-associated cellular alteration in a variety of post-mitotic cells of many species. These pigments are observed within granules composed, in part, of damaged protein and lipid. In the present mini-review, I provide a comprehensive summary of fluorescent adducts originated from malondialdehyde (MDA).

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