Synthesis, characterization and free radical scavenging activity of modified silica-naringin hybrid system

Abstract

This study aimed to develop a procedure for preparing a modified silica-naringin hybrid system. To accomplish, the properties of the obtained material were characterized by FT-IR analysis, UV-Vis spectrophotometry, thermogravimetry, scanning electron microscopy (SEM), and zeta potential. 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay was used to characterize and evaluate the antioxidant activity. The naringin release profile at pH = 1.2 and 7.2 were determined. FT-IR studies confirmed the interaction between the naringin and present carrier. The release study indicated that a release an approximately 20% and 50% of the release occurred in the first 30 min in pH = 1.2 and 7.2, respectively. The thermogravimetry and UV-Vis spectrophotometry analysis allowed us to determine the amount of naringin in the studied hybrid material at the level of several percent. The proposed hybrid material shows good stability, as evidenced by the zeta potential of about +30 and −30 mV in an acidic and alkaline environment, respectively. Antioxidant properties are comparable to those of pure naringin. The results suggest that the obtained hybrid material is a promising product with antioxidant properties.

Keywords:

• Naringin
• hybrid system
• silica
• amine modification
• antioxidant

Disclosure statement

The authors report no conflict of interest. The authors alone are responsible for the content and writing of this article.

Additional information

Funding

This study received financial support from the Polish Ministry of Science and Higher Education for the Faculty of Chemistry of Adam Mickiewicz University in Poznan under statutory activity subsidies.