Oral health in patients with stroke: a meta-analysis of comparative studies

ABSTRACT

Objective: This meta-analysis systematically analyzed and compared oral health between stroke patients and controls.

Data source: The electronic databases of PubMed, EMBASE, PsycINFO, Medline and Web of Science were independently searched by two authors from their inception to 14 June 2018.

Study selection: Eleven studies comparing oral health between stroke patients (n = 1,742) and controls (n = 1,193) were analyzed.

Data extraction: The full texts of the 11 studies were independently reviewed. Data on oral health were independently extracted by two authors.

Data synthesis: Mean differences (MD) and 95% confidence intervals (CI) were calculated and synthesized using fixed or random-effects models, as appropriate. Compared to controls, stroke patients had poorer oral health: they had more Dental Caries (5 studies; MD = 2.89, 95% CI: 0.91–4.88, p= .04), but less Remaining Teeth scores (6 studies; MD = −2.93, 95% CI: −3.91, −1.95; p < .00001). Both the Plaque Index (3 studies; MD = 0.21, 95% CI: 0.14, 0.28; p < .00001) and Gingival Index scores (4 studies; MD = 0.22, 95% CI: 0.14, 0.30; p < .00001) were significantly higher in stroke patients, indicating worse periodontal status.

Conclusions: Stroke patients had poorer overall oral health status compared to controls. Given the importance of oral health to overall health, further research on screening for oral health problems after stroke should be conducted and effective management strategies should be devised and implemented.

KEYWORDS:

• Oral health
• stroke
• comparative studies

Author contributions

Study design: LNZ, YTX. Data collection, analysis, and interpretation: LNZ, WWR, SHL, QZ. Drafting of the manuscript: LNZ, WWR, SHL, BJH, QZ. Revision of the manuscript: BJH and GSU. Approval of the final version for publication: all co-authors.

Additional information

Funding

[MYRG2015-00230-FHS; MYRG2016-00005-FHS], National Key Research & Development Program of China [No. 2016YFC1307200], Beijing Municipal Administration of Hospitals Clinical Medicine Development of Special Funding Support [No.ZYLX201607]; and Beijing Municipal Administration of Hospitals’ Ascent Plan [No. DFL20151801].