Assessment of Antibacterial Activity of Solanum surrattense Against Waterborne Pathogens Isolated from Surface Drinking Water of the Potohar Region in Pakistan

ABSTRACT

People dwelling in different cities of the Potohar region, Pakistan, are mostly dependent on surface water for drinking and domestic use. In an attempt to make available potable, safe water, filtration plants were constructed along with dams in the Potohar region. Water samples from these filtration plants were collected and analyzed for total and faecal coliform bacteria as well as for total viable count. Results showed that bacterial indicators of faecal contamination were numerous and significantly greater than World Health Organization recommended guidelines. Accordingly, antibacterial activity of methanolic and aqueous extracts of different parts of Solanum surrattense were assessed in vitro against waterborne pathogens. Fruits exhibited more antibacterial activities at incubation at 37°C than shoots and roots, which showed lowest Minimum Inhibitory Concentration (MIC) and zones of inhibition. These results suggest that plants offer a great potential for purification of drinking water that needs to be explored further because fruit extract of the aforementioned plant can be of practical use against waterborne pathogens.

Key Words:

• Faecal Coliforms
• antibacterial activity
• waterborne pathogens
• dams of Potohar region
• Solanum surrattense

ACKNOWLEDGMENTS

The authors thankfully acknowledge the contribution of all the persons working in different government departments for providing necessary information and Drug Control & Traditional Medicine Division (DC & TMD), National Institute of Health (NIH), for providing laboratory facilities.

Notes

**Supplying water after proper treatment.