Residual Pattern and Dietary Intake of Iprodione on Grapes under Egyptian Field Conditions: A Prelude to Risk Assessment Profile

ABSTRACT

Field experiments were conducted in two different locations in the Nile delta to determine the residue levels and dissipation rates of iprodione in grapes. Iprodione was applied in different rates (recommended dose and two times recommended dose) and spraying times. Analysis was carried out using liquid chromatography-tandem mass spectrometry (LC-MS/MS). The dissipation rates of iprodione were described using first-order kinetics and the half-life ranged from 8.8 to 9.4 days. There was a sharp decrease in the amount of iprodione residues 10 days after application. At harvest time, the remaining residues of iprodione were below the Food and Agriculture Organization (FAO)/World Health Organization (WHO) maximum residue level (MRL) of 10 mg/kg when measured 14 days after final application. The exposure to iprodione was assessed and compared to acceptable daily intake (ADI). Based on grape consumption, the estimated daily intakes of iprodione ranged from 0.2% to 1.1% of the ADI, showing insignificant risk to consumers.

Key Words:

• iprodione
• residues
• dissipation pattern
• LC-MS/MS
• grapes
• daily intake