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Articles

Cholesterol removal by Β-cyclodextrin modified cryogel column

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Abstract

In this presented work, synthesis of poly(HEMA-GMA) cryogel, its modification with β-cyclodextrin and its usability for cholesterol removal were investigated. For this, cryogels were prepared by cryocopolymerization technique and modified covalently by β-cyclodextrin. Prepared cryogels were characterized by FTIR, SEM studies and swelling test. Maximum cholesterol adsorption efficiency of the β-cyclodextrin immobilized poly(HEMA-GMA) cryogel was found to be as 291 mg/g cryogel. These β-cyclodextrin functionalized cryogels were used repeatedly for 50 times without any significant decrease in their cholesterol recognition capability. Cholesterol removal efficiency of the β-cyclodextrin immobilized poly(HEMA-GMA) cryogel was also tested from egg yolk, milk and artificial human serum samples.

Graphical Abstract

Acknowledgment

This research has been supported by the Adnan Menderes University Research Fund under project number FEF-17037.

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