Methods for Assay and Related Substances in Nitrendipine Raw Materials

N. Beaulieu Bureau of Drug Research Health Protection Branch Tunney's Pasture Ottawa, Ontario, K1A OL2, Canada

R. W. Sears Bureau of Drug Research Health Protection Branch Tunney's Pasture Ottawa, Ontario, K1A OL2, Canada

E. G. Lovering Bureau of Drug Research Health Protection Branch Tunney's Pasture Ottawa, Ontario, K1A OL2, Canada

Abstract

A liquid chromatographic method has been developed for the determination of nitrendipine and related compounds in drug raw material. The method resolves the available related compounds from the drug and each other. The limit of quantitation for the related compounds is about 0.05%.

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Methods for Assay and Related Substances in Nitrendipine Raw Materials

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Methods for Assay and Related Substances in Nitrendipine Raw Materials

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