Catalytic Oxidation of Triphenyl Phosphite with Ferric Ion-Modified Chromatographic Silica

Abstract

Triphenyl phosphite oxidation to triphenyl phosphate has found to be catalyzed by ferric ion-modified silica station phases in liquid chromatographic columns. The oxidation chemrist. found in this study indicates that special precautions are need for aromatic phosphite analyses where columns may contain metals leached from stainless steel equipment. The catalytic activity be suppressed by inert gas purging of the mobile phase to reduce. its oxygen content and treating the column with a reductant deactivate stationary phase oxidative sites. The activity can restored by treating the deactivated column with appropriate oxidants. The on-column triphenyl phosphite oxidation reaction can be used as a diagnostic tool to provide evidence on column contaminations with immobilized active metals and their loca within the column. Using the ideal liquid chromatographic reactor model with an inert standard method, kinetic parameters for the column triphenyl phosphite oxidation reaction can be evaluate.