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Original Articles

Enantiomer Separation by Electrochromatography in Open Tubular Columns Coated with Chirasil-Dex

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Pages 915-931 | Published online: 23 Sep 2006
 

Abstract

The possibility of chiral interactions in a 50 μm i.d. open tubular column was created by coating the inner surface with an immobilizable dimethylpolysilo-xane containing chemically bonded permethylated β- or γ-cyclodextrin (CHIRA-SIL-DEX). This chiral stationary phase was employed for the separation of the enantiomers of NSAIDs and small molecules by the principle of electrochro-matography under various conditions.

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