Abstract
Two racemic compounds, namely N-(3,5-dinitrobenzoyl)-tert-butylvallnamide, and N-(3,5-dinitrobenzoyl)-tert-butylleucinamide, have been successfully completely resolved by centrifugal partition chromatography, using N-dodecanoyl-L-Proline-3,5-dimethylanilide as a chiral selector, and a biphasic system made with heptane, ethyl acetate, methanol and water. This opens the way to a better understanding of this class of separation by centrifugal partition chromatography.