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Abstract
A rapid method for the analysis of the contrast agent iopamidol (isovue)in serum by CE is described. The method involves deproteinzation with acetonitrile to remove serum proteins followed by direct capillary zone electrophoresis. It is rapid(about 10 min) and sensitive. Other contrast agents and compounds used for renal function tests such as iohexol, iothalamic acid and p-aminohippuric acid can be detected by the same method. The use of acetonitrile in this method to remove serum proteins results in sample stacking allowing the detection of levels less than 1 mg/L.