Advanced search
Publication Cover
Prehospital Emergency Care Volume 23, 2019 - Issue 4
Submit an article Journal homepage
531
Views
2
CrossRef citations to date
0
Altmetric
Original Contributions

Intraosseous Administration of Tissue Plasminogen Activator on a Mobile Stroke Unit

Ritvij BowryCorrespondence[email protected]
, MD,
May Nour
, MD,
Teresa Kus
, MPH,
Stephanie Parker
, RN,
Jonathan Stephenson
, RN,
Jeffrey Saver
, MD ORCID Icon,
James C. Grotta
, MD &
Daniel Ostermayer
, MD show all
Pages 447-452 | Published online: 25 Oct 2018
 
Sample our Medicine, Dentistry, Nursing & Allied Health journals, sign in here to start your FREE access for 14 days

Abstract

Objective: Mobile stroke units offer improved time to administration of thrombolytics for ischemic stroke patients. Acquisition of intravenous (IV) access, however, can be challenging in the prehospital environment leading to treatment delays. Intraosseous (IO) access is commonly used in the prehospital setting for a variety of conditions and may serve as a viable means for tPA (tissue plasminogen activator) administration. Methods/Results: We describe 3 cases in which tPA was administered via IO access on a mobile stroke unit as part of the Benefits of Stroke Treatment Delivered Using a Mobile Stroke Unit Compared to Standard Management by Emergency Medical Services (BEST-MSU) trial. Conclusion: No adverse events were observed in the process of obtaining IO access or administering tPA.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related Research Data

Un syndrome des loges secondaire à la pose d’un cathéter intra-osseux
Source: Elsevier BV
Use of intra-osseous access in adults: a systematic review
Source: HAL CCSD
a prospective study
Source: Ovid Technologies (Wolters Kluwer Health)
Benefits of stroke treatment delivered using a mobile stroke unit trial
Source: SAGE Publications
Prehospital Advanced Diagnostics and Treatment of Acute Stroke: Protocol for a Controlled Intervention Study.
Source: JMIR Publications Inc.
Complication of intraosseous administration of systemic fibrinolysis for a massive pulmonary embolism with cardiac arrest.
Source: Elsevier BV
A Serious Adult Intraosseous Catheter Complication and Review of the Literature
Source: Ovid Technologies (Wolters Kluwer Health)
A Prospective In-Field Comparison of Intravenous Line Placement by Urban and Nonurban Emergency Medical Services Personnel
Source: Elsevier BV
Systemic Fibrinolysis Through Intraosseous Vascular Access in ST-Segment Elevation Myocardial Infarction
Source: Elsevier BV
Rapid and equivalent systemic bioavailability of the antidotes HI-6 and dicobalt edetate via the intraosseous and intravenous routes.
Source: BMJ
Prothrombin complex concentrate administration through intraosseous access for reversal of rivaroxaban
Source: Elsevier BV
The use of intraosseous needles for injection of contrast media for computed tomographic angiography of the thoracic aorta
Source: Elsevier BV
Rapid and Complete Bioavailability of Antidotes for Organophosphorus Nerve Agent and Cyanide Poisoning in Minipigs After Intraosseous Administration
Source: Elsevier BV
Current advances in intraosseous infusion – A systematic review
Source: Elsevier BV
No intravenous access, no problem: Intraosseous administration of tranexamic acid is as effective as intravenous in a porcine hemorrhage model.
Source: Ovid Technologies (Wolters Kluwer Health)
A Prehospital Acute Neurological Treatment and Optimization of Medical Care in Stroke (PHANTOM-S) Substudy
Source: American Medical Association (AMA)
Intraosseous administration of thrombolysis in out-of-hospital massive pulmonary thromboembolism.
Source: BMJ
Intraosseous versus intravenous vascular access during out-of-hospital cardiac arrest: a randomized controlled trial.
Source: Elsevier BV
Efficacy and safety of the EZ-IO™ intraosseous device: Out-of-hospital implementation of a management algorithm for difficult vascular access.
Source: Elsevier BV

Linking provided by 

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.