Short Synthesis of 3‐Prenylcoumarins by an Unusual Prenylation

Abstract

Prenylation of coumarins that have hydroxyl or alkoxyl or halo substitution (1a–1i) using 2‐methyl‐3‐butene‐2‐ol in the presence of boron trifluoride formed 3‐prenylcoumarins (2a–2d).

Laila Impex communication no. 44.

Keywords:

• 2‐Methyl‐3‐butene‐2‐ol
• prenylation
• 3‐prenylcoumarin
• synthesis

Acknowledgments

The authors thank T.‐S. Wu and A. G. Damu, National Cheng Kung University, Taiwan, and Sophisticated Instrumentation Facility (SIF), Bangalore, for NMR spectral data and Sri G. Ganga Raju, chairman, Laila Group, for his encouragement.

Notes

Laila Impex communication no. 44.