Study on Subchronic Toxicity of Chlorine Dioxide and By-Products in Water

Abstract

Subchronic toxicity of the mixture of ClO₂, ClO₂ ⁻ and ClO₃ ⁻ in water on rat was studied through feeding test for 90 days. Statistical analyses of variance on weight gained, food utilization efficiency, indexes of blood and serum, liver/bodyweight and kidney/bodyweight ratios, and histopathological examination on liver and kidney were carried out. The results showed that solution of ClO₂ and its by-products ClO₂ ⁻ and ClO₃ ⁻ at a concentration of 553 mg/L was not toxic.

Keywords:

• Chlorine dioxide
• Chlorite
• Chlorate
• Toxicity

Notes

*1. blank group; 4. high-dosage group.