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Journal of Environmental Science and Health . Part A: Environmental Science and Engineering Volume 17, 1982 - Issue 4: Exposure to Environmental Agents, Their Metabolism, and Mechanisms of Toxicity
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Mechanisms of toxicity/carcinogenicity

Estimating the carcinogenetic effects on humans of low doses of radiation or chemicals

R. B. Setlow Biology Department, Brookhaven National Laboratory, Upton, NY, 11973
Pages 599-603 | Published online: 15 Dec 2008
 
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Abstract

Our knowledge of DNA repair is briefly summarized. It is proposed that a knowledge of the concentration of DNA adducts as a function of dose is essential for the extrapolation of carcinogenic dose‐response data to low doses.

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