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Abstract
The class of aryl sulfonamides was studied in order to nominate chemicals to the Chemical Selection Working Group as candidates for carcinogenesis bioassay. After application of several qualifying criteria relating to previous, current, or planned carcinogenicity tests and to commercial significance, the preliminary candidate list of 189 chemicals was reduced to a list of 89 chemicals. Based upon consideration of both the suspicion of possible carcinogenic activity and evidence indicating potential exposure, the following five chemicals were nominated: sulfanilamide, sulfamethazine, sulfathiazole, sulfamethizole, and salicylazosulfapyridine.
Notes
Reprints may be obtained from Dr. C.T. Helmes and also from Dr. H. F. Kraybill; Scientific Coordinator for the Office of Environmental Cancer, Division of Cancer Cause and Prevention, National Cancer Institute, Landow Building Room C337, 7910 Woodmont Avenue, Bethesda, Maryland 20205