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Journal of Environmental Science and Health . Part A: Environmental Science and Engineering and Toxicology Volume 26, 1991 - Issue 8
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Toxic & Hazardous substance control

Pharmaco‐toxicological aspects of carcinogenic tryptophan pyrolysis products in the environment

Shigeo Manabe Department of Hygiene & Preventive Medicine, Faculty of Medicine, University of Tokyo, 7–3–1 Hongo, Bunkyo‐ku, Tokyo, 113, Japan
,
Osamu Wada Department of Hygiene & Preventive Medicine, Faculty of Medicine, University of Tokyo, 7–3–1 Hongo, Bunkyo‐ku, Tokyo, 113, Japan
&
Yoshikatsu Kanai Department of Hygiene & Preventive Medicine, Faculty of Medicine, University of Tokyo, 7–3–1 Hongo, Bunkyo‐ku, Tokyo, 113, Japan
Pages 1449-1469 | Received 30 Jul 1990, Accepted 21 Dec 1990, Published online: 15 Dec 2008
 
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Abstract

During the last decade a new series of mutagenic and carcinogenic heterocyclic amines has been isolated from pyrolysates of amino acids and proteins. Among them carcinogenic tryptophan pyrolysis products have been investigated from various points of view, and useful pieces of information have been collected. The purpose of this report is to summarize data on carcinogenic tryptophan pyrolsis products.

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