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Abstract
The effects of cadmium on the uterus of rabbits were studied by light microscopy with morphometry. The experiment involved 32 animals. Cadmium was applied intraperitoneally (i.p.) to group A (1.5 mg/kg body weight), perorally (p.o.) to group B (1.0 mg/kg b.w.) for a 5‐month period, and also p.o. (1.0 mg/kg b.w.) for a 5‐month period of application followed by a 7‐month cessation of application for group C. All experimental groups were compared to a control group (K), as well as to other experimental groups. Animals were examined after the experimental period.
In the uterus, the amount of endometrium was in the range of 48.42% to 50.37%, and that of myometrium of 51.58% to 49.63%. The percentage of glandular epithelium in the endometrium was significantly lower in group A in comparison with group C (P<0.05). Amount of stroma was significantly higher in the group receiving i.p., in comparison with the group receiving p.o. administration for a 5‐month period (P<0.01). From the photographed pictures edematization of uterus with desintegrations in the blood vessel wall and subsequent diapedesis were evident.