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ABSTRACT
Background
None of the various treatment modalities for failed back surgery syndrome (FBSS) is satisfactory.
Aim of the study
Comparison of subjective and laboratory outcomes of the 3-in-1 procedure to percutaneous screw and rod spinal fixation (PSRF) for FBSS patients determined at the end of Phase II of the study (3-year follow-up after surgery).
Patients & Methods
This is phase II (follow-up at 3 years) of patients undergoing 3-in-1 procedure (Group B) or PSRF (Group A) as regard pain and disability scores and cytokines levels.
Results
At phase of the study, pain and disability scores were still significantly lower in all patients with significantly lower scores in group B than in group A. In comparison to the results obtained at the end of Phase I, the 3-in-1 procedure provided better outcome than PSRF only and number of patients graded the outcome as excellent-to-good was significantly higher than in patients of group B than group A. At the end of both phases, serum inflammatory cytokines’ levels were significantly decreased and anti-inflammatory cytokines’ levels were significantly increased in all patients compared to preoperative levels with significant difference in favor of patients of group B. the percentages of change in pain and disability scores at end of Phase II were significantly correlated with the percentage of change of serum anti-inflammatory cytokines’ levels in both groups.
Conclusion
After 36 m after the 3-in-1 procedure pain scores were significantly decreased with improved disability scores and inflammatory milieu than in patients having FBSS only.
Disclosure statement
No potential conflict of interest was reported by the author(s).
Declaration
The Authors declare that there is no conflict of interest.