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Journal of Chemotherapy Volume 1, 1989 - Issue 4
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Original Articles

Low Dose Intermittent 5-Fluorouracil, Epirubicin and Cyclophosphamide (FEC) in Poor Risk Patients with Advanced Transitional Cell Bladder Cancer: a Pilot Study

G. LelliOncology Department, S. Orsola-Malpighi Hospital, Bologna.
,
A. TononiOncology Department, S. Orsola-Malpighi Hospital, Bologna.
,
P. BacchettiI Urology Department, S. Orsola-Malpighi Hospital, Bologna.
,
P. MaverI Urology Department, S. Orsola-Malpighi Hospital, Bologna.
,
G. CorradoI Urology Department, S. Orsola-Malpighi Hospital, Bologna.
,
F. GarofaloII Urology Department, S. Orsola-Malpighi Hospital, Bologna.
,
P. De SantisII Urology Department, S. Orsola-Malpighi Hospital, Bologna.
&
F. PannutiOncology Department, S. Orsola-Malpighi Hospital, Bologna.
 show all
Pages 269-271 | Published online: 14 Jul 2016
 
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Summary

Fifteen patients with locally advanced or metastatic bladder carcinoma and with cardiac and/or renal impairment were treated with a combination of 5-fluorouracil, 400 mg/m2, epirubicin, 40 mg/m2, and cyclophosphamide, 400 mg/m2. No complete or partial remissions were observed among the 14 evaluable patients. The toxicity level was very low. We are now trying to «tailor» platinum-based combinations to renal function.

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