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Original Articles

Dermatophytosis in Egypt with Special Reference to Immunological Studies on Patients with Trichophyton Violaceum Infection

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Pages 52-54 | Published online: 15 Apr 2014
 

ABSTRACT

228 patients clinically diagnosed as superficial fungus infections (115 scaly ringworm of the scalp, 13 black dot, 9 favus, 9 kerion, 48 tinea corporis, 18 tinea cruris, 9 onychomycosis, 5 tinea pedis and 2 tinea barbae) were examined mycologically. 30 cases with T. Violaceum infection were examined immunologically. T. violaceum was the most common dermatophyte (45.6%), T. rubrum (5.3%), T. schoenleinii (4.8), T. mentagrophytes (3.5%) and E. floccosum (1.8%). In 30 cases with T. violaceum infection there was a significant decrease in Erosette particularly in chronic cases. The helper/suppressor ratio of T-lymphocytes (detected by monoclonal antibodies) in patients was 0.99:1 while in control cases it was 1.6:1. There was a marked increase in IgM and IgG but not in IgA levels. The C3c fraction of the complement showed a slight decrease and C4 a marked decrease in comparison with the control.

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