An Approach for Optimal Control of Fed-Batch Fermentation Process with Multi Control Variables

ABSTRACT

In this paper a fermentation process of E. Coli production is presented by using real laboratory experimental data. The adequate model of the process is proved. An effective algorithm for process optimization in the presence of three optimal control variables: rotation speed, gas flow rate and substratum floating rate is developed by using a modified approach of method of the dynamic programming. The analysis of results shows that the complex investigation with more control variables vastly raises efficiency of the process.