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ABSTRACT
Oral condyloma acuminatum is a papillomatous lesion that is transmitted most often sexually and associated with the human papilloma virus (HPV). This report describes a case of a 30-year-old woman with multiple oral condylomata acuminata, located on the lateral edges and on the dorsum of the tongue. The incisional biopsy showed histological features compatible with those of condyloma acuminatum. E6 viral oncogene of HPV types 6, 11, 16, and 33 was identified by means of polymerase chain reaction (PCR). The lesions were removed by radiodissecation and treated topically with trichloroacetic acid (80% and 40%) and interferon-alpha-2a. No recurrence was evident 8 months after the treatment. We report this case not only for the simultaneous presence of low- and high- risk HPV types in one patient and the rarity of the condition, but also for the good response to the combined surgical and medical treatment that we observed.