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ABSTRACT
A new 'family” of drugs, the piperazines, has emerged on the European drug market as new designer drugs for the last few years. The key members of the group that have been used for non-medical recreational purposes are BZP (Benzylpiperazine, A2, Frenzy, Nemesis), TFMPP (1-[3-(trifluoro-methyl)phenyl]piperazine), mCPP (meta-chlorophenylpiperazine, 1-(3-Chlorophenyl)-piperazine). Piperazines are psychoactive drugs and clearly not without risks. With stimulant effects comparable to amphetamines but with a lower potency and differential global scheduling status, they have been sold as a supposed legal alternative to ecstasy. Currently, in Bulgaria these piperazines are not controlled drugs. Other European countries have banned or are going to ban some piperazines. This review provides a summary of current knowledge on recreational piperazines, the current situation in the Bulgaria and the experience in some countries.