ABSTRACT
Here we study the distribution of three HIV-1 resistance conferring polymorphisms—CCR5del32, CCR2-64I and SDF1-3'A in Bulgarian population uninfected with HIV. The relative risk of onset of AIDS symptoms (RRA) is calculated based on this distribution in a representative group of Bulgarians (n=95). RRA was detected to be 0.85 - which falls into the range of this characteristic for the Europeans. The relative risk values similar to that of RRA might be helpful in assessing specific epidemiological situations in population groups, especially when human genetic factors are involved.