ABSTRACT
Continuous intoxication with heavy metals seems to be the major problem of the modern societies, which results most of the morphologic-physiological, as well as genetic anomaly in plants. The aim of this study is to analyze intoxicated tobacco material (Nicotiana tabacum L.) with heavy metals (copper, cadmium, lead) and overdoses of fungicide (Ridomil gold) for enzymatic (catalase activity) and biopigment activity (chloroplast pigments) and to make morpho-anatomic examinations (lateral cut of stem and leaf). The plants were from the crop 2008 of two oriental (half oriental) types: PRILEP (P-156) and JAKA (Jv-125/3). They were cultivated in controlled experimental conditions in the Botanical Garden by the Department of Botany, Institute of Biology, Faculty of Natural Sciences and Mathematics-Skopje. Analysis material was taken from leaves in the first insertion or lower leaves (I phase).