Lymphocyte DNA adducts and polymorphism in the DNA repair enzyme XPD

Masayoshi Ichiba, Jiusong Zhang, Chikako Kiyohara, Yoichi Nakanishi, Koichi Takayama, Nobuyuki Hara, Masafumi Enoki, Katsumaro Tomokuni Department of Community Health Science, Saga Medical School, Nabeshima, Saga 849-8501, Japan. e-mail: [email protected]; Department of Preventive Medicine, Division of Social Medicine, Graduate School of Medical Science, Kyushu University, Maidashi, Higashiku, Fukuoka 812-8582, Japan; Research Institute for Disease of the Chest, Graduate School of Medical Science, Kyushu University, Maidashi, Higashiku, Fukuoka 812-8582, Japan

Abstract

The effect of genetic polymorphism of DNA repair enzyme on the DNA adduct levels was evaluated in this study. We explored the relationship between polymorphism in the nucleotide excision repair enzyme XPD and DNA adduct levels in lymphocytes. Lymphocyte DNA adducts were measured by a ³²

Keywords::

Dna Adduct Repair

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Lymphocyte DNA adducts and polymorphism in the DNA repair enzyme XPD

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Lymphocyte DNA adducts and polymorphism in the DNA repair enzyme XPD

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