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Research Article

Soluble CD40 ligand in haemodialysis patients: survival impact and cardiovascular prognostic role

, , , , , , , & show all
Pages 232-238 | Received 22 Apr 2015, Accepted 07 Apr 2016, Published online: 29 Jun 2016
 

Abstract

Context: Soluble CD40 ligand (sCD40l) can predict cardiovascular events (CVE) and mortality in haemodialysis (HD) patients (short-, medium-term follow-up studies).

Objective: To evaluate the relationship between sCD40l and survival, CVE and mortality in HD patients on long-term follow-up.

Methods: We registered 46 HD patients’ baseline characteristics, mortality and CVE for 108 months.

Results: SCD40l correlated positively with C-reactive protein, was higher in survivors, but had no impact on survival and was not predictive for CVE or CV mortality.

Conclusion: The levels of sCD40l have no influence on survival or CVE and mortality in HD patients in a long-term follow-up.

Disclosure statement

The authors report no declarations of interest.

Funding information

This paper was published under the frame of European Social Fund, Human Resources Development Operational Programme 2007–2013, project no POSDRU/159/1.5/S/138776.

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