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Neurocase
Behavior, Cognition and Neuroscience
Volume 13, 2007 - Issue 3
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Original Articles

Effect of the Cold Pressor Test on Memory and Cognitive Flexibility

Kelly Ishizuka Department of Neurosurgery, University of Minnesota, MN, USA; Department of Neurology, Neuroscience Graduate Studies Program, The Ohio State University, Columbus, OH, USA
,
Ashleigh Hillier Department of Psychology, University of Massachusetts, Lowell, MA, USA; Department of Neurology, Neuroscience Graduate Studies Program, The Ohio State University, Columbus, OH, USA
&
David Q. Beversdorf Department of Neurology, Neuroscience Graduate Studies Program, The Ohio State University, Columbus, OH, USACorrespondence[email protected]
Pages 154-157 | Received 22 Feb 2007, Accepted 07 May 2007, Published online: 04 Sep 2007
 
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Abstract

Cognitive flexibility is affected by stress. The cold pressor test is a known adrenergic stressor that impairs memory, but the effect on cognitive flexibility is unknown. Sixteen subjects were given cognitive flexibility and memory tasks with and without one hand immersed in cold water. Memory was impaired in the cold pressor condition but there was no effect on cognitive flexibility. The lack of a cold pressor effect on cognitive flexibility may result from an isolated effect on the peripheral noradrenergic system, whereas indirect effects due to nociception on memory may occur.

This research was funded in part by grants from NIDA (R21 DA015734) and NINDS (K23 NS43222) (DQB). Portions of this research were presented at the Cognitive Neuroscience Society, 2003. Kelly Ishizuka was funded by the Roessler Scholarship Fund of Ohio State University.

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