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Neurocase
Behavior, Cognition and Neuroscience
Volume 23, 2017 - Issue 1
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Acute severe depression induced by stimulation of the right globus pallidus internus

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Pages 84-87 | Received 21 Dec 2015, Accepted 16 Jan 2017, Published online: 06 Feb 2017
 

ABSTRACT

Depressive symptoms may occur after Deep Brain Stimulation (DBS) in the subthalamic nucleus. This is often explained by reduced pharmacological treatment after surgery, and not as a direct effect of DBS. Pallidal DBS seems not to be associated with such side effects and have not, to our knowledge, previously been reported. We present a patient with acute depressive symptoms induced by pallidal DBS. We believe this case strengthen the hypothesis that the basal ganglia and structures involved in the functional connectome of these nucleuses play a role not only in regulation of movement but also in regulation of mood.

Disclosure statement

No potential conflict of interest was reported by the authors.

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