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ABSTRACT
This case study presents a patient with early-onset Alzheimer`s disease, who applied transcranial direct current stimulation (tDCS) daily for 8 consecutive months. This was a much higher frequency than previous tDCS studies. Neuropsychological assessments were conducted before the first tDCS session, after 5 months and after 8 months. After 8 months, the patient’s immediate recall improved with 39%, whereas delayed recall improved 23%. Overall, the results revealed that patient’s cognitive functions were stabilized. There may be slight possibility that tDCS could slow the cognitive decline in Alzheimer`s disease. This should be investigated in clinical trials.
Acknowledgment
The authors would like to thank technician Thomas Nermo for technical support and the patient for his participation.
Disclosure statement
No potential conflict of interest was reported by the authors.
Additional information
Funding
Notes on contributors
Martin Bystad
MB planned the study, collected data, drafted the manuscript, and analyzed the data. IDR planned the study and drafted the manuscript. OG drafted the manuscript and analyzed the data. PMA drafted the manuscript, analyzed data, and planned the study. All authors read and approved the final manuscript.
Ingrid Daae Rasmussen
MB planned the study, collected data, drafted the manuscript, and analyzed the data. IDR planned the study and drafted the manuscript. OG drafted the manuscript and analyzed the data. PMA drafted the manuscript, analyzed data, and planned the study. All authors read and approved the final manuscript.
Ole Grønli
MB planned the study, collected data, drafted the manuscript, and analyzed the data. IDR planned the study and drafted the manuscript. OG drafted the manuscript and analyzed the data. PMA drafted the manuscript, analyzed data, and planned the study. All authors read and approved the final manuscript.
Per M. Aslaksen
MB planned the study, collected data, drafted the manuscript, and analyzed the data. IDR planned the study and drafted the manuscript. OG drafted the manuscript and analyzed the data. PMA drafted the manuscript, analyzed data, and planned the study. All authors read and approved the final manuscript.