Neurocase

Behavior, Cognition and Neuroscience

Volume 28, 2022 - Issue 2

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Research Article

The Role of the Insula in Classical and Dissociative PTSD: A Double Case Study

Robin Bladesa Neurological Associates – The Interventional Group, Los Angeles, California, USACorrespondence[email protected]

https://orcid.org/0000-0001-8700-5290

Sergio Becerraa Neurological Associates – The Interventional Group, Los Angeles, California, USA

Sheldon Jordana Neurological Associates – The Interventional Group, Los Angeles, California, USA;b Department of Neurology, University of California Los Angeles, Los Angeles, California, USA

Branon Eusebioc Theramind, Santa Barbara, California, USA

Mark Heatwolec Theramind, Santa Barbara, California, USA

Jessica Iovinea Neurological Associates – The Interventional Group, Los Angeles, California, USA

Kennedy Mahdavia Neurological Associates – The Interventional Group, Los Angeles, California, USA

Michael Mamound CNS Health, Los Angeles, California, USA

Natalie Nicodemusa Neurological Associates – The Interventional Group, Los Angeles, California, USA

Hannah Packhama Neurological Associates – The Interventional Group, Los Angeles, California, USA

Norman Spivake Department of Neurosurgery, University of California Los Angeles, Los Angeles, California, USA

Taylor Kuhnf Department of Psychiatry and Biobehavioral Sciences, University of California Los Angeles, Los Angeles, California, USA

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ABSTRACT

Two service members were diagnosed with PTSD due to military trauma exposure. One presented with the classical manifestation; the other presented with the dissociative subtype. A statistical map revealed anterior localization of insula connectivity in the classical PTSD patient and posterior localization in the dissociative PTSD patient. These differences suggest that dissociative PTSD may be identified, understood, and treated as a disorder related to increased posterior insula connectivity. This double case study provides preliminary evidence for a concrete neuroanatomical discrepancy between insula function in classical and dissociative PTSD that may help explain the emergence of different coping strategies.

KEYWORDS:

All procedures followed were in accordance with the ethical standards of the responsible committee on human experimentation (institutional and national) and with the Helsinki Declaration of 1975, and the applicable revisions at the time of the investigation. Informed consent was obtained from all patients for being included in the study.

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The Role of the Insula in Classical and Dissociative PTSD: A Double Case Study

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The Role of the Insula in Classical and Dissociative PTSD: A Double Case Study

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