Abstract
A 5-year-old male child presented with convulsive seizures, mental retardation and cutaneous angiofibroma of about 4 years' duration. A physical examination revealed that he was unable to sit up, stand and walk. He had fine wart-like lesions on the cheek and forehead. A systemic examination showed no abnormality. A computerized axial tomography scan revealed calcification at the head of the right caudate nucleus without associated edema. Irregular calcification was also seen adjacent to the posterior part of the body of the left lateral ventricle. He showed improvement in mental deficiency and seizures on treatment with coenzyme Q10 (90 mg day 4 ) and fish oil (Eicosapataenoic acid (EPA) 1.08 g + Docosahaexenoic acid (DHA) 0.72 g day -1 ) within 12 weeks of follow-up.