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Cognition and Ageing

Analysis of genetic and environmental correlation between leisure activities and cognitive function in aging Chinese twins

, , , , , , & show all
Pages 493-498 | Received 16 Jul 2020, Accepted 23 Nov 2020, Published online: 09 Dec 2020
 

Abstract

Objective

Leisure activity has been shown to be beneficial to mental health and cognitive aging. The biological basis of the correlation is, however, poorly understood. This study aimed at exploring the genetic and environmental impacts on correlation between leisure activities and cognitive function in the Chinese middle- and old-aged twins.

Methods

Cognition measured using a screening test (Montreal Cognitive Assessment, MoCA) and leisure activities including intellectual and social activity were investigated on 379 complete twin pairs of middle- and old-aged twins. Univariate and bivariate twin models were fitted to estimate the genetic and environmental components in their variance and covariance.

Results

Moderate heritability was estimated for leisure activities and cognition (0.44–0.53) but insignificant for social activity. Common environmental factors accounted for about 0.36 of the total variance to social activity with no significant contribution to leisure activity, intellectual activity and cognition. Unique environmental factors displayed moderate contributions (0.47–0.64) to leisure activities and cognition. Bivariate analysis showed highly and positively genetic correlations between leisure activities and cognition (rG=0.80–0.96). Besides, intellectual activity and cognition presented low but significant unique environmental correlation (rE=0.12).

Conclusions

Genetic factor had the moderate contribution to leisure activities and cognition. Cognitive function was highly genetically related to leisure activities. Intellectual activity and cognitive function may share some unique environmental basis.

Disclosure statement

No potential conflict of interest was reported by the authors.

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Additional information

Funding

This study was supported by National Natural Science Foundation of China (31371024)

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