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Original Articles

A review of factors that moderate autobiographical memory performance in patients with major depressive disorder

, , , , &
Pages 1122-1144 | Received 17 Aug 2009, Accepted 15 Mar 2010, Published online: 09 Jun 2010
 

Abstract

Studies of autobiographical recall in patients with major depressive disorder (MDD) reveal overgeneralization, where autobiographical memory (AM) comprises primarily factual or repeated information as opposed to details specific in time and in place and definitive of episodic re-experiencing. In addition to reviewing AM impairment in MDD, we explore the contribution of key method, demographic, and clinical variables to this dysfunction. Several candidate variables emerge, including testing method, emotion, mood state, illness burden, medication status, electroconvulsive therapy (ECT), comorbidity, trauma, age, ruminative state, and executive and memory function. These variables appear to interact in a complex manner to influence AM performance in MDD.

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