![Sample our Medicine, Dentistry, Nursing & Allied Health journals, sign in here to start your FREE access for 14 days]({"type":"image" , "src" : "/sda/5944/TOC-Subject-Sample-2021-Medicine-Dentistry-Nursing-Allied-Health.jpg"})
Abstract
Context: Essential oils from Pinus species have been reported to have various therapeutic properties.
Objective: This study was undertaken to identify the chemical composition and cytoprotective effects of the essential oil of Pinus halepensis L. against aspirin-induced damage in cells in vitro.
Material and methods: The cytoprotection of the oil against toxicity of aspirin on the small intestine epithelial cells IEC-6 was tested.
Results: The obtained results have shown that 35 different compounds were identified. Aspirin induced a decrease in cell viability, and exhibited significant damage to their morphology and an increase in superoxide dismutase (SOD) and catalase (CAT) activities. However, the co-treatment of aspirin with the essential oil of Pinus induced a significant increase in cell viability and a decrease in SOD and CAT activities.
Conclusion: Overall, these finding suggest that the essential oil of Pinus halepensis L. has potent cytoprotective effect against aspirin-induced toxicity in IEC-6 cells.
Acknowledgements
We express our sincere thanks and gratitude to laboratory of ORPHY, UFR Sciences et Technique, Faculty of Medicine and Health Sciences, University of Western Brittany, France, for their help. The authors would like to thank Mrs Leila Mahfoudi, a teacher of English, for her diligent professional English language editing which significantly contributed to the completion of this work.
Disclosure statement
The authors declare that there is no conflict of interest.