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Archives of Physiology and Biochemistry
The Journal of Metabolic Diseases
Volume 128, 2022 - Issue 2
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Original Articles

Diagnostic and prognostic value of new bioscore in critically ill septic patients

Pinar Sena Department of Infectious Diseases and Clinical Microbiology, Izmir Katip Celebi University Ataturk Training and Research Hospital, Karabaglar/Izmir, TurkeyCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0003-1365-3329
ORCID Icon,
Tuna Demirdala Department of Infectious Diseases and Clinical Microbiology, Izmir Katip Celebi University Ataturk Training and Research Hospital, Karabaglar/Izmir, TurkeyORCID Iconhttps://orcid.org/0000-0002-9046-5666
ORCID Icon,
Salih Atakan Nemlia Department of Infectious Diseases and Clinical Microbiology, Izmir Katip Celebi University Ataturk Training and Research Hospital, Karabaglar/Izmir, TurkeyORCID Iconhttps://orcid.org/0000-0002-2720-9870
ORCID Icon &
Atilla Sencanb Department of Anesthesiology and Reanimation, Izmir Katip Celebi University Ataturk Training and Research Hospital, Karabaglar/Izmir, TurkeyORCID Iconhttps://orcid.org/0000-0002-3765-9891
ORCID Icon
Pages 300-305 | Received 24 Jun 2019, Accepted 02 Oct 2019, Published online: 05 Nov 2019
 
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Abstract

Objective

To evaluate the diagnostic and prognostic value of biomarkers and new bioscore in septic patients in intensive care unit (ICU).

Materials and methods

A study was conducted on septic and non-septic patients in ICU. Diagnostic and prognostic values of C-reactive protein (CRP), procalcitonin (PCT), Sequential Organ Failure Assessments (SOFA) score and new bioscore were analysed statistically.

Results

A total of 226 patients were enrolled in the study. In septic patients, PCT, SOFA and bioscore were found significantly increased (p = .007, p = .001 and p = .001, respectively). The AUC value of bioscore was higher than PCT and SOFA in septic patients. SOFA was found to be more significant prognostic marker than bioscore in predicting 28-day mortality. The prognostic value of bioscore and SOFA was similar for predicting 90-day mortality.

Conclusions

The new bioscore formed by combination of CRP, PCT and SOFA score may be useful in early diagnosis of sepsis.

Disclosure statement

The authors declare that there is no conflict of interest.

Author contributions

P. S. designed the study. P. S., T. D., S. A. N. and A. S. researched the data. P. S. and T. D. analysed the data statistically. P. S. and T. D. prepared the manuscript. P. S., T. D., S. A. N. and A. S. reviewed the manuscript. All authors approved the final form of manuscript.

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Related Research Data

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