Screening of Southeastern Brazilian Mikania. Species on Trypanosoma cruzi.

Juliana Siqueira Chaves Departamento de Física e Química, Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP, Brazil

Andréa Mendes do Nascimento Departamento de Física e Química, Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP, Brazil

Adriana Pereira Soares Departamento de Física e Química, Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP, Brazil

Luciana Mattoso Pires de Campos Departamento de Física e Química, Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP, Brazil

Patrícia Abrão de Oliveira Departamento de Química, Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP, Brazil

Sérgio de Albuquerque Departamento de Análises Clínicas, Toxicológicas e Bromatológicas, Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP, Brazil

Dionéia Camilo Rodrigues de Oliveira Departamento de Física e Química, Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP, Brazil

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Abstract

Southeastern Brazilian Mikania. (Asteraceae) species were evaluated for trypanocidal activity against the trypomastigote forms of Trypanosoma cruzi.at a concentration of 4000 µg/mL. Fourteen extracts were examined for in vitro. trypanocidal properties. Of total extracts, 92.9% (13 extracts) exhibited trypanocidal effects. The dichloromethane extract of Mikania camporum. B. Robinson and the methanol extract of Mikania micrantha. H. B. K. caused 100% lysis of the parasites.

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Screening of Southeastern Brazilian Mikania. Species on Trypanosoma cruzi.

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Screening of Southeastern Brazilian Mikania. Species on Trypanosoma cruzi.

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