Role of 18-fluoro-2-deoxyglucose positron emission tomography in detecting acute inflammatory lesions of non-bacterial osteitis in patients with a fever of unknown origin: A comparative study of 18-fluoro-2-deoxyglucose positron emission tomography, bone scan, and magnetic resonance imaging

Abstract

We report three patients with non-bacterial osteitis (NBO) who had fever of unknown origin (FUO) as an initial symptom. 18-Fluoro-2-deoxyglucose positron emission tomography (¹⁸F-FDG–PET) can be used to detect acute inflammatory lesions. There seems to be variation among the results of ¹⁸F-FDG–PET, a bone scan, and magnetic resonance imaging (MRI). Therefore, it would be useful to perform a bone scan to detect all lesions, combined with MRI to confirm the diagnosis of NBO, followed by ¹⁸F-FDG–PET.

Keywords:

• Fever of unknown origin
• 18-Fluoro-2-deoxyglucose positron emission tomography
• Non-bacterial osteitis